个人简历
马丝曼，女，讲师，博士研究生
科学研究方向
手性药物的分离及立体选择性PK-PD研究，
中药复方对神经性疾病的药效及机理研究
联系方式：
Email: mandy13188204161@163.com
通讯：贵州省贵安新区安康大道6号贵州医科大学，561113
简历
2017.06毕业于沈阳药科大学，获理学学士学位；2021.06年毕业于沈阳药科大学，获分析化学理学学士学位；2024.06年毕业于沈阳药科大学，获药物分析学理学学士学位。同年8月就职于贵州医科大学药学院。
近三年负责科研课题
1、国家自然科学基金青年项目《矿物药铁霜通过上调GR-HSP90复合物抑制神经元损伤改善抑郁症的机理研究》，参与，No. 82003971。
代表性论文
1.Ma Siman, Xin Hao, Zhao Pengfei, Feng Shiwen, Chen Jialin, Yin Shiliang, Wei Yanan, Shi Yitong, Jin Ge, Di Xin, Zhang Hong. Comprehensive Stereoselectivity Assessment of Toxicokinetics, Tissue Distribution, Cytotoxicity, and Environmental Fate of Chiral Pesticide Propiconazole,Journal of Agricultural and Food Chemistry. 2023 Dec 13;71(49):19760-19771
2.Ma Siman, Wang Lina, Guo Guoxian, Yu Jia, Di Xin. Systematic Stereoselectivity Evaluations of Tetramethrin Enantiomers: Stereoselective Cytotoxicity, Metabolism, and Environmental Fate in Earthworms, Soils, Vegetables, Fruits,Journal of Agricultural and Food Chemistry. 2023 Jan 11;71(1):234-243
3.Ma Siman, Zhang Hong, Li Fei, Zhao Pengfei, Yin Shiliang, Sun Jiaqi, Xu Jiayu, Wang Zhenqi, Xu Xin, Di Xin. Systemic Stereoselectivity Study of Fenobucarb: Environmental Behaviors in Greenhouse Vegetables, Fruits, Earthworms, and Soils and Its Cytotoxicity,Journal of Agricultural and Food Chemistry. 2022 Feb 23;70(7):2127-2135.
4. Ma Siman, Lun Jia, Liu Yanru, Jiang Zhen, Guo Xingjie. Enantioseparation and Determination of Penconazole in Rat Plasma by Chiral LC-MS/MS: Application to a Stereoselective Toxicokinetic Study,Molecules. 2020 Jun 28;25(13):2964.
5.Ma Siman, Wang Lina, Guo Guoxian, Tang Jing, Yu Jia. The enantioseparation and determination of sulconazole enantiomers in rat plasma and tissues by a chiral HPLC–ESI–MS/MS method and its application to studies on stereoselective pharmacokinetics and tissue distribution,New Journal of Chemistry. 2022,46, 4262-4271
6.Ma Siman, Wang Lina, Guo Guoxian, Tang Jing, Yu Jia, GuoXingjie. Solid phase extraction procedure coupled with the chiral LC-ESI-MS/MS method for the enantioseparation and determination of butoconazole enantiomers in rat plasma and tissues: application to the enantioselective study on pharmacokinetics and tissue distribution,New Journal of Chemistry. 2021,45, 1317-1326.
